il-6, il-10 and il-17 gene polymorphisms in iranian women with recurrent miscarriage

IL-6, IL-10 and IL-17 Gene Polymorphisms in Iranian Women with Recurrent Miscarriage

Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 A/C, -819 C/T, -1082 A/G), IL-6 (-174 C/G) and IL-17 (-197 G/A) in Iranian women. Method: Po...

Evaluation of IL-17 and IL-10 Production in Infectious Mononucleosis in EBV Patients

Epstein–Barr virus is primarily the cause of acute infectious mononucleosis and can also cause lymphoma and autoimmune diseases. Th17 cells, which are a unique subset of ThCD4+ cells, direct the infection toward inflammation through production of inflammatory cytokine IL-17. In contrast, Treg Foxp3 cells inhibit inflammation through secretion of anti-inflammatory cytokine IL-10, leading to chro...

reviews Title : IL 17 A and IL 17 F gene polymorphisms in patients with rheumatoid arthritis

Polymorphisms of interleukin (IL)-1a, IL-1h, IL-6, IL-10, and IL-18 and the risk of ovarian cancer

Objective. Recent studies of ovarian cancer have suggested a role for inflammation in carcinogenesis. Data from a population-based casecontrol study in Hawaii were examined to assess the relation between polymorphisms in cytokines involved with the inflammatory response, specifically members of the interleukin (IL) family and the incidence of ovarian cancer. Patients and methods. The analysis o...

Negative Association of Serum IL-6 and IL-17 with Type-II Diabetes Retinopathy

Background: Diabetes mellitus (DM) is a health concern which leads to complications such as retinopathy. Pakistan has 6.9 million people living with DM and this toll will be doubled by 2025. Objective: To determine serum IL-6 and IL-17 of type 2 diabetes mellitus (T2DM) patients with retinopathy. Methods: In this cross-sectional casecontrol study, 212 subjects enrolled which were categorized in...

IL-6 and IL-10 promoter gene polymorphisms in psoriasis vulgaris.

Overexpression of IL-6 has been implicated in the pathology of numerous autoimmune and chronic inflammatory diseases, including psoriasis, and relative deficiency of IL-10 in psoriatic patients seems to be important in the development of this disease. The aim of this study was to investigate the association between IL-6 and IL-10 single nucleotide polymorphisms and susceptibility to psoriasis v...